Best 25p Cyclotron

A cost effective cyclotron system for both PET and SPECT imaging compounds

Best 25p with Shields Small cyclotrons that produce FDG are designed to take advantage of production reactions that are optimum at low cyclotron energies.  Because of their size, this class of cyclotron is called a "Baby Cyclotron".  Many Baby Cyclotrons have limitations in energy or intensity for the production of SPECT radioisotopes.  TeamBest® introduced the B25p cyclotron, a mid range cyclotron that is capable of producing commercial quantities of both PET and SPECT radio-compounds.  The output from the B25P is ideal for regional radio-pharmacy applications as well as groups requiring sustained SPECT compound supply.

Shown in the above right photo is a BEST 25 MeV cyclotron with four production targets mounted within their own local shielding.  This configuration allows Fluorine-18 production on two independent targets as well as two additional target stations for SPECT radio-isotope production.  This configuration allows the cyclotron and production targets to be enclosed in a single shielded vault and is cost effective for regional facilities.

Best 25p with Beam Line As the demand for special radioisotopes increases, a beam line extension can be installed in the shielded vault for dedicated production stations.  This will allow higher production rates when the demand merits with only modest facility changes.

A beam-line to a dedicated shielded area can also be included, as demand increases, by modest changes to the facility.  The cyclotron vault is changed by including a beam line and a separation barrier between the dedicated production target and the rest of the cyclotron area.

Though no longer in the Baby Cyclotron category, the B25p requires only a modest increase in infrastructure from the smaller PET cyclotron.  The facility construction and operation costs are more in line with Baby Cyclotron facilities that laboratories that support the entire country or more!

TeamBest® offers full facility design and implementation support.  Production targets using metal, gas and liquid target material together with their separation processes are available from TeamBest®.  Service is provided from the TeamBest® offices throughout the country and the world.

External Production Targets

The cyclotron is supplied with two 18F production targets complete with loading and routing to the production hot cell.  Targets for 18F, 11C, 13N, 15O, 64Cu, 124I, 103Pd and 99mTc are available.

High current solid target stations (10 kW) and high current gas target stations (4 kW) are available upon request.

Click here to download the product sheet (PDF).


Best 25p Map Type of Cyclotron

  • Negative hydrogen ion (H-)
  • External ion source, multi-cusp 5 mA
  • Simultaneous dual beam extraction (multiple foil extraction cartridge)
  • Standard:  2 target stations on each side of the cyclotron (total of 4 target stations)
  • Optional:  2 beam lines (with additional beam lines routes downstream of the extracted beam)

Beam Current

  • 400 µA extracted beam current
  • Higher currents available upon request

Beam Energy

  • 15 to 25 MeV variable energy extraction
  • 20 MeV fixed energy extraction (optional)


  • Magnet coil:  ˜56 kAT
  • Weight:  ˜30 tons
  • Geometry:  4 sectors

RF System

  • Resonator:  2 Dees
  • Dee Voltage:  60 kV
  • RF frequency:  74 MHz, 4th harmonic
  • Power required:  25 kW (nominal)
  • Energy gain per turn:  240 keV

Vacuum System

  • Base pressure:  <2 x 10−7 Torr
  • Operating pressure:  <1 x 10−6 Torr
  • Pumps:  Cryogenic pump system

Automated Control System

  • Computer system:  Standard PC, Windows−based OS
  • Controllers:  Siemens Industrial PLC Modules
  • User console:  Color monitor
  • Interface:  Graphical user interface
  • Networking:  Standard thin-wire Ethernet hardware