A cost effective cyclotron system for both PET and SPECT imaging compounds
Small cyclotrons that produce FDG are designed to take advantage of
production reactions that are optimum at low cyclotron energies. Because of their size,
this class of cyclotron is called a "Baby Cyclotron". Many Baby Cyclotrons have
limitations in energy or intensity for the production of SPECT radioisotopes.
TeamBest® introduced the B25p cyclotron, a mid range
cyclotron that is capable of producing commercial quantities of both PET and SPECT
radio-compounds. The output from the B25P is ideal for regional radio-pharmacy
applications as well as groups requiring sustained SPECT compound supply.
Shown in the above right photo is a BEST 25 MeV cyclotron with four production
targets mounted within their own local shielding. This configuration allows Fluorine-18
production on two independent targets as well as two additional target stations for SPECT
radio-isotope production. This configuration allows the cyclotron and production targets
to be enclosed in a single shielded vault and is cost effective for regional facilities.
As the demand for special radioisotopes increases, a beam line extension
can be installed in the shielded vault for dedicated production stations. This will allow
higher production rates when the demand merits with only modest facility changes.
A beam-line to a dedicated shielded area can also be included, as demand
increases, by modest changes to the facility. The cyclotron vault
is changed by including a beam line and a separation barrier between the dedicated production
target and the rest of the cyclotron area.
Though no longer in the Baby Cyclotron category, the B25p requires
only a modest increase in infrastructure from the smaller PET cyclotron. The facility
construction and operation costs are more in line with Baby Cyclotron facilities that
laboratories that support the entire country or more!
TeamBest® offers full facility design and implementation support.
Production targets using metal, gas and liquid target material together
with their separation processes are available from TeamBest®.
Service is provided from the TeamBest® offices throughout the
country and the world.
External Production Targets
The cyclotron is supplied with two 18F production targets complete with loading
and routing to the production hot cell. Targets for 18F, 11C,
13N, 15O, 64Cu,
124I, 103Pd and
99mTc are available.
High current solid target stations (10 kW) and high current gas target stations (4 kW) are available upon request.