TeamBest®, through Best Cyclotron Systems
(BCS), offers radioisotopes and production capabilities for nuclear medicine and radiotherapy with its range
of cyclotron systems. BCS’s mission is to create technology to provide healthcare options for various
needs around the world. Our staff assists from the planning stage, detailed design, facility
construction, daily production, maintenance and emergency repair through the
TeamBest® network. We provide solutions
for PET-CT and molecular imaging radiopharmaceuticals with the same excellent customized care as
demonstrated in our 40+ year history of radiotherapy support.
BCS Cyclotron Systems
BCS staff works with the end user to configure the system for the needs of the user. There are now six general energy domains for BCS cyclotron systems: 7.5, 9.5, 15, 25, 35 and 70 MeV. The applications for these accelerator systems are different, and the configurations will reflect that difference.
For more information on these products, please read the appropriate descriptions below:
The Best 15p is a 15 MeV proton cyclotron. 15 MeV has been selected to offer a significant 18Fluorine production yield with the investment efficiency of small power costs and low initial cost. As the user moves to other PET radioisotopes, the energy offers adequate production yields of radioisotopes such as 18F and 64Cu with the added benefit of optimized specific activity of the product. The cyclotron system has a small footprint and can be either installed in its own shielded room with or without local shielding (reduces radiation) or can be shielded with integrated (self) shielding. Production targets for 18F, 11C, 13N, 15O and 64Cu are available. These systems are designed for individual hospital or small regional pharmacy use.
The Best 25p is a 25 MeV proton cyclotron. It is designed to provide additional proton energy to make some specific single photon (SPECT) radioisotopes available for users. Most notable is 123I, where the majority of production yield is covered by the 25 MeV energy beam. A group producing a specific radiopharmaceutical can, with the Best 25p, produce their own input material to maintain independence and cost-effective manufacturing. The key feature is a unique design for each application that streamlines cost and production efficiency.
The Best 35p is a 35 MeV proton cyclotron. It is designed to produce radioisotopes using the (p,2n) or the (p,3n) reaction. There is a broad range of single photon emitters that are used in nuclear diagnostic imaging and therapy that are accessible in this energy range. TeamBest will partner with the end user to create a facility that will satisfy the end user's requirements and provide some of TeamBest's radioisotope supply requirements. Both solid and gas target systems can be added to the Best 35p system.
The Best 70p is a 70 MeV proton cyclotron. The energy provides access to radionuclides produced by (p,xn) reactions and is a research accelerator as well as a radioisotope production cyclotron. TeamBest will partner with the end user to create a facility that will satisfy the end user's requirements and provide some of TeamBest's radioisotope supply requirements, together with the opportunity for joint research projects. Both solid and gas target systems can be added to the Best 70p system.
The B-100 Biomarker Generator is a revolutionary development in radiopharmaceutical production that delivers a single or batch dose of [18F]FDG, and additional advanced [18F] biomarkers, "on demand". The system provides integration of all components needed to produce and qualify PET biomarkers...
The B200 is a sub-compact, self-shielded 9.5 MeV cyclotron. Features include a low energy compact system, allowing it to be placed next to a PET/CT, plus a chemistry module, easy to operate push-button graphic interface and much more. Isotopes it is capable of producing include 18FDG, Na18F, 18F−MISO, 18FLT, 18F−Choline, 18F−DOPA, 18F−PSMA, 11C, 13N and 68Ga.